Use of a web site in a multicenter plastic surgery trial: a new option for data acquisition.
نویسندگان
چکیده
Randomized multicenter clinical trials for the study of certain conditions with low prevalence in the population, and rapid enrollment of a sufficient number of patients in a short time to evaluate a new technique, are major needs in medical research. A multicenter clinical trial allows the researchers who are interested in a particular problem to collect data from several different hospitals all over the world in a single database. This minimizes selection bias through the analysis of a large and representative sample.1 At the moment, the exchange of data among research centers involved in a multicenter study is becoming too slow and expensive for the rapid development of today’s medicine. Too many complex, expensive, and unreliable methods are used to collect data.2 The World Wide Web enables people to communicate in real time and to access a great deal of information.3 We studied a method to collect data from a large group of researchers through this efficient tool. The development of a Web site for data collection of a research project in the controversial field of mammary implants, in particular those prefilled with a carboxy-methylcellulose hydrogel, is here described. The main objective of this project, named Multicenter Hydrogel Group, is a multicenter evaluation study of the validity of these new mammary implants as determined by the frequency of a major complication, capsular contracture. We felt the need for Web data acquisition to rapidly provide a large sample, with an adequate follow-up, through immediate and easy information exchange among different centers. We discuss the security of an Internet database and a simple five-level security method developed from our group.
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عنوان ژورنال:
- Plastic and reconstructive surgery
دوره 109 5 شماره
صفحات -
تاریخ انتشار 2002